期刊简介
《中国组织工程研究与临床康复》(原《中国临床康复》)杂志系卫生部主管,中国康复医学会、《中国组织工程研究与临床康复》杂志社主办的国家级学术期刊。经新出报刊[2006]288号批准,《中国临床康复》更名为《中国组织工程研究与临床康复》,变更后国内统一连续出版物号为CN 21-1539/R,ISSN 1673-8225,国内外公开发行,发行代号8-584,周刊,200页/期,A4开本。 更名后的《中国组织工程研究与临床康复》推出2009年的全新策划,年出版53期,各周刊征稿重点邀您参与,请您评估。网址:www.crter.org
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首页>中国组织工程研究杂志

- 杂志名称:中国组织工程研究杂志
- 主管单位:中华人民共和国卫生部
- 主办单位:中国康复医学会,《中国组织工程研究与临床康复》杂志社
- 国际刊号:2095-4344
- 国内刊号:21-1581/R
- 出版周期:周刊
期刊荣誉:百种中国杰出学术期刊期刊收录:维普收录(中), 北大核心期刊(中国人文社会科学核心期刊), 知网收录(中), 统计源核心期刊(中国科技论文核心期刊), 剑桥科学文摘, 万方收录(中)
糖尿病大鼠缺血再灌注损伤中性白细胞的作用
王文安;任惠民;吕传真
关键词:diabetes mellitus, neutrophil, cerebral ischemia/reperfusion
摘要:Objective To explore the role of neutrophil in focal cerebral injury of ischemia/reperfused diabetic rats.Methods The infarction size in diabetic and non diabetic rats with ischemia for 1h/reperfusion for 24 h was evaluated by 2,3,5 triphenyl tetrazolium chloride (TTC) staining.The magnitude of cerebral neutrophil infiltration was quantified by measuring myeloperoxidase (MPO) activity of brain tissue in all rats with ischemia for 1h/ reperfused various periods by the method of enzymology.Results The infarction size in the ipsilateral hemisphere of diabetic rats were more significant than that in the normal rats (P< 0.05).The activity of myeloperoxidase (MPO) in the former was also higher than that in the latter (P< 0.05).Conclusions Diabetes could exacerbate inflammatory response to cerebral ischemia reperfusion and thereby aggravate cerebral injury of ischemia/reperfusion.
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