期刊简介
《中国组织工程研究与临床康复》（原《中国临床康复》）杂志系卫生部主管，中国康复医学会、《中国组织工程研究与临床康复》杂志社主办的国家级学术期刊。经新出报刊[2006]288号批准，《中国临床康复》更名为《中国组织工程研究与临床康复》，变更后国内统一连续出版物号为CN 21-1539/R，ISSN 1673-8225，国内外公开发行，发行代号8-584，周刊，200页/期，A4开本。 更名后的《中国组织工程研究与临床康复》推出2009年的全新策划,年出版53期,各周刊征稿重点邀您参与,请您评估。网址：www.crter.org
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首页>中国组织工程研究杂志
- 杂志名称：中国组织工程研究杂志
- 主管单位：中华人民共和国卫生部
- 主办单位：中国康复医学会,《中国组织工程研究与临床康复》杂志社
- 国际刊号：2095-4344
- 国内刊号：21-1581/R
- 出版周期：周刊
期刊荣誉：百种中国杰出学术期刊期刊收录：维普收录(中), 北大核心期刊(中国人文社会科学核心期刊), 知网收录(中), 统计源核心期刊(中国科技论文核心期刊), 剑桥科学文摘, 万方收录(中)
网状减张小切口缝合法提高大鼠背部张力皮瓣存活机制
年申生；吴岳嵩；苏佳灿；侯铁胜；张春才
关键词：meshed relaxing short incisions, surgical skin flap, endothelins, Immunohistochemistry
摘要：Objective To observe effects of meshed relaxing short incisions (MRSI) on the content of endothelin (ET) in rat tension skin flap,and to investigate the mechanism of meshed relaxing short incisions(MRSI) on wound healing process of tension skin flap.Method We designed an experimental model to investigate the change of ET content caused by MRSI and observe the distribution of ET in rat skin flap tissue each period of wound healing.In the meantime,the immunohistochemistry and auto image analysis were employed.Results Our results showed:(1) ET positive immunologic reaction granules involved in small vascular endothelial cell in rat skin flap tissue increased with prolonging of time within 3 days;(2) the content of ET in MRSI group were significant lower than that of hypertension group (P< 0.05) .Conclusion The decrease of ET contents may be one of the causes that MRSI improves microcirculation of skin flap, and reduces edema and facilitates healing of skin flap.
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